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doi:10.1093/aje/kws342 Weaver TE, Maislin G, Dinges DF, et al

the BDNF paradox (SSRIs generally raise BDNF and hippocampal neurogenesis via 5-HT1A/5-HT4 signalling, so antidepressant fog is not a synapse-deficiency a peptide refills)

In fact, peroxides have a biphasic effect on Wnt signaling with an increase 20 min after activation and reduced signaling some hours later (57)

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The authors conclude that given the extremely low mortality risk of a locally recurrent LM, a strategy of excision, purse string, imiquimod 5xw for 8 w then ex with 2mm minimises morbidity, reduces margin by 71% and final defect size by 74%